SAINTS boss Paul Wellens has named his 21-man squad for Friday's final regular round of Super League at Leigh Sports Village.
If Saints beat the Leopards they will climb into the top four and gain a home semi-final.
If they lose then then they will qualify in sixth and likely then travel to Warrington in the knockout next week.
Wellens said: "We gained a bit of confidence off the performance last week and we obviously managed to score a few points there, and looked a bit more threatening with the ball than we have done in recent weeks.
"Obviously the challenge steps up again this weekend, against a good side, a really competitive side who in recent times we've always had tough battles with.
"Whenever we play Leigh we always have a really tough game against them and it's got that real derby feel to it and I'm sure this weekend will be no different.
"Obviously there's a lot to play for both teams, which obviously makes for a great occasion and we are excited about the opportunity.
"We want to keep building on our performance and keep finding improvements.
"We know as a collective that we need to find improvements if we want to achieve our ambitions this year."
Wellens makes one change to the squad from Castleford, with Moses Mbye available for selection after serving a one-match penalty notice.
Wing Tee Ritson is is left out from the previous 21-man squad selection.
St Helens 21-man squad v. Leigh Leopards, Super League Round 27.
1.Jack Welsby, 2. Tommy Makinson, 3. Waqa Blake, 4. Mark Percival, 5. Jon Bennison, 6. Jonny Lomax, 7. Lewis Dodd, 8. Alex Walmsley, 9. Daryl Clark, 10. Matty Lees, 11. Sione Mata’utia, 12. Joe Batchelor, 13. Morgan Knowles, 14. Moses Mbye, 17. Agnatius Paasi, 19. Matt Whitley, 20. George Delaney, 21. Ben Davies, 24. Jake Burns, 30. Jonny Vaughan, 31. Noah Stephens.
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