The draw has been made for the fifth round of the Carnegie Challenge Cup.
Defending champions St Helens face a home tie against local rivals Warrington Wolves, whilst last year's beaten finalists Catalans Dragons face an away trip to Bradford Bulls.
In total there are four all engage Super League ties with the others being Harlequins RL against Leeds Rhinos and Hull KR versus Huddersfield Giants.
At least one team from either The Co-operative National League One or Two will make the Quarter Finals after Dewsbury Rams were drawn against Oldham.
Ties from the fifth round of the Carnegie Challenge Cup will be played on the weekend of 10 and 11 May.
The two televised ties will be St Helens V Warrington Wolves on Saturday 10 May (BBC 1, kick off 15:00) and Hull KR V Huddersfield Giants on Sunday 11 May (BBC 2, kick off 13:15) This year's final will be played at Wembley Stadium on Saturday 30 August.
The full draw is: Hull KR V Huddersfield Giants.
Barrow Raiders V Wakefield Wildcats.
Dewsbury Rams V Oldham.
Bradford Bulls V Catalans Dragons.
Wigan Warriors V Whitehaven.
Widnes Vikings V Hull FC.
Harlequins RL V Leeds Rhinos.
St Helens V Warrington Wolves.